Hypometabolic patterns of focal cortical dysplasia in PET-MRI co-registration imaging: a retrospective evaluation in a series of 83 patients

Objective To characterize the PET-MRI co-registration of hypometabolic patterns in focal cortical dysplasia (FCD) types I and II provide some suggestions presurgical evaluation epilepsy surgery. Methods We retrospectively analyzed imaging data from a cohort 83 patients with histologically confirmed FCD II. Hypometabolic were classified into 4 types: bottom sulcus hypometabolism (BOSH), single island (SIOS), gyrus or (SGOS), multiple gyri sulci (MGOS). Results Most cases that overlooked by conventional MRI PET but positive focalized lesions dorsolateral frontal lobe (9/15) type IIa was most prevalent pathological (11/15). The histological ( p = 0.027) locations < 0.001) independent predictors patterns. Focalized (BOSH, SIOS, SGOS) primarily observed (33/39) (43/62) extensive pattern (MGOS) temporal (18/20) (16/21; 0.005). Conclusion enhanced detection compared reading. more than those FCD, respectively. predilection suggested subtle should be checked carefully suspected epilepsy.